"""Bioactive Equivalent Combinatorial Components"" as Defined Labeled Amount of Active Constituents for Quality Control of Traditional Chinese Medicines"
10.11842/wst.2014.03.010
- VernacularTitle:以“等效成分群”为标示量的中药质量控制体系的构建
- Author:
Hua YANG
;
Lianwen QI
;
Huijun LI
;
Ping LI
- Publication Type:Journal Article
- Keywords:
Quality control of traditional Chinese medicines;
bioactive equivalent combinatorial components;
defined labeled amount;
bioactive equivalence oriented feedback screening strategy
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2014;(3):510-513
- CountryChina
- Language:Chinese
-
Abstract:
Quality control and standardization of traditional Chinese medicines (TCMs) is the key to its globalization. Generally, there is a common practice to select one or more compounds as chemical markers for the purpose of qual-ity assessment. However, how to select chemical markers and how to set the range of effective concentrations are still the bottleneck. The authors proposed a bioactive equivalent combinatorial components (BECCs) as defined labeled amount of active constituents oriented quality control strategy of TCMs based on years of research work. Focusing on the relationship between chemical components efficacy and quality of TCMs, this strategy provides a new perspective and methods to improve quality control of TCMs.
