Research on Extraction Process of Zhechong Chuangyu Capsule

VernacularTitle:蟅虫创愈胶囊提取工艺研究
Author: Zhijun YANG ; Zhong JIA ; Wenjun YUAN ; Jing WU
Publication Type:Journal Article
Keywords: Zhechong Chuangyu Capsule; orthogonal experiment; extraction process
From: Chinese Journal of Information on Traditional Chinese Medicine 2014;(6):80-82
CountryChina
Language:Chinese
Abstract: Objective To establish the extraction process of Zhechong Chuangyu Capsule. Methods The difference of analgesic effect of water extraction and alcohol extraction in mice was observed by body-torsion test to determine the extract solvent. With the rate of aqueous extraction, n-butyl alcohol extraction and asperosaponin Ⅵ as evaluating indicator, the influencing factors including solvent volume, time and times of extraction were investegated to evaluate extracting procedure by orthogonal experiment. Results There was no obvious difference in analgesic effect between water extraction and alcohol extraction. Given the requirement of produce, aqueous extraction was a better choice. The optimum extracting condition was extracted 3 times with 20 folds volume of solvent, and extraction time was 150 minutes. Conclusion The extraction process is feasible to be applied into production.