The Clinical Meaning of Testing Serum MCP-1 and Homocysteine Level on Angina

VernacularTitle:检测血清MCP-1和同型半胱氨酸水平对心绞痛的临床意义
Author: Jumin BAO
Publication Type:Journal Article
Keywords: SA; UA; MCP-1; HCY
From: Journal of Zhejiang Chinese Medical University 2014;(3):306-308
CountryChina
Language:Chinese
Abstract: [Objective] To study the difference between stable angina(SA) and unstable angina(UA) on monocyte chemoattractant protein-1(MCP-1)and homocysteine(HCY)concentrations, to define its clinical meaning to angina. [Method] Select 67 cases of UA and 65 cases of SA, take 60 normal persons of similar age as healthy control group; col ect the vein blood within 12h at the last attack of UA group, col ect the vein blood in early morning for SA group and control one; measure serum MCP-1 and HCY with ELISA method. [Result] The MCP-1 and HCY levels had difference among al groups, among which, groups UA and SA were higher than control one, with difference of statistical meaning; while UA group was higher than SA group, with difference of statistical meaning. [Conclusion] In angina patients, the serum inflammatory factors MCP-1 and HCY levels are higher than healthy persons, UA higher than SA patients;to test MCP-1 and HCY levels is helpful to identifying and screening high-risk angina patients.