Comparison of different scoring systems evaluating short-term prognosis of patients with hepatitis B associated acute hepatic failure
10.3969/j.issn.1006-5725.2014.04.023
- VernacularTitle:不同评分系统对乙肝相关慢加急性肝衰竭患者短期预后评估的比较
- Author:
Lei LIU
;
Fengmei WAGN
;
Zhichao KAN
;
Yan LI
;
Shixiang XIAO
;
Hua LIU
;
Ying LI
- Publication Type:Journal Article
- Keywords:
Scoring system;
Acute on chronic liver failure;
Prognosis;
receiver operating characteristic curve (ROC curve);
area under the curve (AUC)
- From:
The Journal of Practical Medicine
2014;(4):571-573
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assessment short-term prognosis in patients with acute on chronic liver failure , several scoring systems were compared. Methods Two hundred and sixteen patients with acute on chronic liver failure were divided into survival group and death group according to the results of 90 days after admission.CTP , MELD,APACHEⅡ, SOFA and SMSVH score were calculated.After ROC curves were performed ,the areas under the curves of these scoring systems were compared. Results The areas under the ROC curves of MELD, APACHEⅡ, SOFA, CTP and SMSVH were 0.88, 0.76, 0.89,0.79and 0.69,respectively. The areas under the curves of SOFA and MELD were larger than the APACHEⅡ, CTP and SMSVH (P<0.05). There was no difference between the SOFA and MELD (P>0.05). The area under the curve of CTP was larger than the APACHEⅡ, but there was no statistically significant difference (P > 0.05). The area under the curve of SMSVH were less than 0.7. Conclusions The SOFA, MELD,CTP and APACHEⅡcan predict the short-term prognosis of acute on chronic liver failure. The SOFA and MELD are the best scoring systems.CTP,APACHEⅡ are better than SMSVH. SMSVH fail to predict the prognosis of acute on chronic liver failure.
