Clinical study on the treatment of vitiligo with two narrow band ultraviolet LED combined with drugs
10.3969/J.ISSN.1672-8270.2014.04.033
- VernacularTitle:两种波长LED窄谱紫外线联合药物治疗白癜风的临床疗效研究
- Author:
Rui XU
- Publication Type:Journal Article
- Keywords:
Ultraviolet LED;
Drug;
Vitiligo;
Therapeutic effect
- From:
China Medical Equipment
2014;(4):90-92
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the clinical curative effect of narrow-band UVB-LED (308nm) combined with tacrolimus, narrow-band UVA-LED (365nm) combined with 8-Methoxypsoralen irradiation in the treatment of vitiligo.Methods: Sixty-four cases of vitiligo patients were chosen and randomly divided into control group and observation group, each group with 32 cases. The control group received 308nm narrow-band UVB-LED irradiation combined with tacrolimus,the observation group received 365nm narrow-band UVA-LED irradiation combined with 8-Methoxypsoralen, the time of appreance of the first pigment island in patients were compared between the two groups,the clinical curative effect of both groups were observed when treated with 10 times and 20 times.Results: The average irradiation times when first pigment island appreance in the observation group and the control group were 5.59 and 6.24 respectively, the difference was not statistically significant (t=1.772,P>0.05). The efficiency rate of the control group was 37.50% after 20 times treatment, and in the observation group was 40.63%, the difference was not statistically significant (x2=0.000,P>0.05).Conclusion: 308nm narrow band UVB-LED combined with tacrolimus and 365nm narrow-band UVA- LED combined with 8- Methoxypsoralen irradiation in the treatment of vitiligo have significant treatment effects, how to improve the treatment effect still need further study.
