Advances in Studies on RKIP and MMP-9 in Colorectal Cancer
10.3969/j.issn.1008-7125.2014.05.010
- VernacularTitle:RKIP 和 MMP-9在结直肠癌中的研究进展
- Author:
Lanming LOU
;
Liping SHI
;
Xiuwei SUN
- Publication Type:Journal Article
- Keywords:
Raf Kinase Inhibitor Protein;
Matrix Metalloproteinase-9;
Colorectal Neoplasms;
Signal Transduction
- From:Chinese Journal of Gastroenterology
2014;(5):294-296
- CountryChina
- Language:Chinese
-
Abstract:
Raf kinase inhibitor protein (RKIP)is a member of the phosphatidylethanolamine-binding protein family, which can inhibit the metastasis of tumor cells and is closely associated with the occurrence and development of tumor. Matrix metalloproteinase-9 (MMP-9)is a endopeptidase that can degrade extracellular matrix and plays an important role in invasion and metastasis of tumor.This article reviewed the advances in studies on RKIP and MMP-9 in colorectal cancer.