Analysis on the distribution of pathogens in intensive care units and their drug resistance
10.3969/j.issn.1673-4130.2014.09.022
- VernacularTitle:重症监护病房病原菌分布及其耐药情况分析
- Author:
Yanjun LI
;
Qiangyuan ZHAO
;
Xiuhong HAO
;
Yanghui QIAN
;
Yiwei DING
;
Xiaoyan LI
- Publication Type:Journal Article
- Keywords:
intensive care units;
pathogens;
drug resistance
- From:
International Journal of Laboratory Medicine
2014;(9):1140-1142
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the distribution of pathogens in intensive care units (ICU ) and their drug resistance . Methods 668 strains of pathogens isolated from specimens from ICU were collected .VITEK 2 Compact automated microbial iden-tification and susceptibility analyzer was utilized to conduct the antimicrobial susceptibility tests .Kirby-Bauer disk diffusion suscep-tibility test(K-B) was employed to conduct the antimicrobial susceptibility test for Gram-negative bacteria cefoperazone/sulbactam . Results 668 strains of pathogens were derived from sputum [434 (65 .0% )] ,blood[83(12 .0% )] ,urine[88(13 .0% )] ,drainage [14(2 .0% )] ,secretions[14(2 .0% )] and other[35(5 .2% )] .Acinetobacter baumannii was the major detected pathogen in Gram-negative bacteria and the resistance rates were over 50% toward other drug excepting levofloxacin ,sulfamethoxazole and amikacin . Staphylococcus Staphylococcus was the major detected pathogen in Gram-positive bacteria and it showed good sensitivity toward ni-trofurantoin ,quinupristin/dalfopristin ,tigecycline and vancomycin .Candida albicans demonstrated the highest detection rate in fun-gi .Conclusion ICU pathogens have drug resistance in serious condition ,and pathogens and drug resistance monitoring should be strengthened .