Research progress of the relationship between miRNAs and pancreatic carcinoma
- VernacularTitle:微小 RNA 与胰腺癌关系研究进展
- Author:
Yingxia HU
;
Hairong ZHANG
- Publication Type:Journal Article
- Keywords:
miRNA;
Pancreatic carcinoma;
Early diagnosis
- From:
Journal of Medical Postgraduates
2014;(4):435-438
- CountryChina
- Language:Chinese
-
Abstract:
MiRNA is a small non-coding single stranded RNA(ssRNA)which is made up by 21~23 nucleotide.This ssRNA has a double effect as tumor suppressor genes and oncogenes , and plays an important role in cell proliferation , differentiation and apop-tosis.Pancreatic carcinoma is a highly malignant tumor with poor prognosis and high mortality rate , and the early diagnosis is difficult . In the last decades , growing studies highlighted the interactions between miRNAs and pancreatic carcinoma .This review provides a re-search overview between miRNAs and pancreatic carcinoma .Meanwhile , the significance of Expression Profile in pancreatic carcinoma′s diagnosis ,treatment and prognosis is also discussed .
