Feasibility of magnetic resonance diffusion-weighted intravoxel incoherent motion imaging and its reproducibility in normal liver
10.3969/j.issn.1002-1671.2014.04.021
- VernacularTitle:正常肝脏体素内不相干运动磁共振扩散加权成像的可行性及可重复性研究
- Author:
Shilin CHEN
;
Xin CHEN
;
Lishan ZHONG
;
Zaiyi LIU
;
Changhong LIANG
- Publication Type:Journal Article
- Keywords:
liver;
magnetic resonance diffusion-weighted imaging;
intravoxel incoherent motion;
reproducibility
- From:
Journal of Practical Radiology
2014;(4):623-626
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the feasibility of magnetic resonance diffusion-weighted intravoxel incoherent motion (DW-IVIM)imaging and its reproducibility in normal liver.Methods Thirty-five young healthy volunteers underwent liver DW-IVIM ex-amination twice on a 1 .5 Tesla Philips MR scanner.Parameter maps of D,D* and f were generated by using a manufacturer-sup-plied software.Six Region-of-interests (ROIs)(3 ROIs in left and right liver lobe,respectively)were drawn on three consecutive middle slices,respectively.The average values of D,D* and f were measured and compared between the left and right liver lobe. The reproducibility of D,D* and f measurement were assessed with Bland-Altman method.Results The values of D,D* and f of left liver lobe [D(×10-3 mm2/s):1.250±0.210,D*(×10-3 mm2/s):101.906±15.063 ,f(%):22.954±5.268]were statistically higher than those of right liver lobe[D(×10-3 mm2/s):1.039±0.124,D*(×10-3 mm2/s):100.127±20.757,f(%),18.317± 3.671](D,f,P<0.001,D*,P<0.232-0.605),however ,their reproducibility of left liver lobe [limit of agreement(LOA):22.55%,51.05%,39.3%,respectively]were lower than those of right liver lobe (LOA:20.3%,39.25%,33.9%).The D values had the best reproducibility in both the left and right liver lobe.Conclusion The liver DW-IVIM is feasible.The values of D,D*and f in left liver lobe were higher that those in right liver lobe but with worse reproducibility of measurement.The D value was most reproducible in both liver lobes.
