Assessment of apparent diffusion coefficient in clinicopathologic and prognostic features of rectal cancer
10.3969/j.issn.1002-1671.2014.05.020
- VernacularTitle:ADC 值评估直肠癌病理及预后的可行性研究
- Author:
Weihuan HOU
;
Jing REN
;
Qi PAN
;
Na LI
;
Huijia LIU
;
Xufang HUANG
;
Zhenhua ZHANG
;
Juntao LU
;
Hong YIN
;
Yi HUAN
- Publication Type:Journal Article
- Keywords:
rectal cancer;
diffusion-weighted imaging;
apparent diffusion coefficient;
prognosis
- From:
Journal of Practical Radiology
2014;(5):795-798
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the value of apparent diffusion coefficient (ADC)in clinic ,pathology and prognosis of rectal cancer. Methods The MRI and DWI findings of 109 patients with pathological proved rectal adenocarcinoma were retrospectively analyzed. DWI with b=0 s/mm2 and b= 1 000 s/mm2 were acquired.Mean tumor ADCs were measured and compared between subgroups stratified by histologic differentiation grades,T-stage,N-stage,mesorectal fascia status and presence of lymphangiovascular or peri-neral invasion.Results Mean tumor ADCs were significantly different when comparing groups stratified by histologic differentiation grades,T-stage,mesorectal fascia status and presence of lymphangiovascular invasion.Tukey’s post hoc test showed that the differences of mean ADCs between good-moderate differentiated group and moderate differentiated group(P =0.996),moderate-poor differentiated group and poor differentiated group(P =0.957)were not significant.The differences among other groups of differentia-tion grades differed significantly(P <0.05).In the T-stage groups,the mean ADCs of T1 stage tumor was significantly higher than that of T3 stage tumor(P <0.05).There were no significant differences among other T-stage groups(P >0.05).There were no sig-nificant differences among N0,N1 and N2 in N-stage groups(P >0.05).Conclusion ADC values can reflect pathologic and prognos-tic features of rectal cancer.
