Anti-inflammatory and the Analgesic Effects of Jiehuo Dieda Ointment
- VernacularTitle:接活跌打膏抗炎镇痛作用考察
- Author:
Bo QIN
;
Gejin WEI
- Publication Type:Journal Article
- Keywords:
Jiehuo dieda ointment;
anti-inflammatory effects;
Analgesia effects
- From:
China Pharmacist
2014;(5):745-747
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the anti-inflammatory and analgesic effects of Jiehuo Dieda ointment. Methods:The anti-inflam-matory activity was observed by rat foot swelling model induced by carrageenan and rat cotton ball granuloma model, and writhing re-sponse in mice induced by acetic acid and hot-plate test were used to explore the analgesic effects. Results:Compared with that of mod-el group, Jiehuo Dieda ointment 28 g·kg-1 ,14 g·kg-1 could significantly decrease rats hind paw swelling rate after 2 hours of ad-ministration. Compared with that of normal control group,Jiehuo Dieda ointment 28 g·kg-1 ,14 g·kg-1 could significantly decrease the weights of rats cotton ball granuloma,could significantly decrease the writhing times ,and increase the pain thresholdr after 60 min of administration(P<0. 05,P<0. 01). Conclusion:Jiehuo Dieda Ointment had obviously anti-inflammatory and analgesia effects.
