Extraction of Total Alkaloids from Yaotong Granules
- VernacularTitle:腰痛颗粒剂中总生物碱的提取工艺研究
- Author:
Yandong YI
;
Guofu HUANG
;
Li DONG
- Publication Type:Journal Article
- Keywords:
Yaotong granules;
Total alkaloids;
Extraction technology;
Orthogonal test
- From:
China Pharmacist
2014;(5):757-760
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the optimum extraction conditions for Yaotong granules. Methods:An orthogonal test was adopted to optimize the percolation extraction process of total alkaloids by orthogonal experiment with the yield of dry extract and total extraction rate of tetrandrine and fangchinoline as the indices. Results:The optimal extraction conditions were as follows:the medicinal materials were soaked with crude powder in 60% ethanol for 48h,then percolated at the rate of 2 ml·min-1 ·kg-1 . Conclusion:The extraction technology for Yaotong granules is simple and rapid with stable results,which can provide theoretical basis for the production of Yaotong granules.