Advances about the role of NGF in angiogenesis
10.3760/cma.j.issn.1673-4203.2014.04.017
- VernacularTitle:神经生长因子在血管生成中的研究进展
- Author:
Lilong GUO
;
Yongjun LI
- Publication Type:Journal Article
- Keywords:
Nerve growth factor;
Neurturin;
Angiogenesis;
Arteriosclerosis obliterans
- From:
International Journal of Surgery
2014;41(4):272-276
- CountryChina
- Language:Chinese
-
Abstract:
Nerve growth factor (NGF) has been the focus in area of angiogenesis.In differential,survival,development of nerves,NGF plays a crucial role.In addition,NGF activates migration,differential of endothelial cells and vascular smooth muscle cells,and stimulate the activation of the endothelial progenitor cells in angiogenesis.Crosstalk between vascular endothelial growth factor and NGF is also critical in the development of vessels.The function of NGF in angiogenesis blazes a trail in therapy of ischemia diseases.
