Exploration of Rational Ethylparaben Contents in Chloramphenicol Eye Drops
- VernacularTitle:氯霉素滴眼液中尼泊金乙酯含量合理性的探讨
- Author:
Huang XIAO
;
Jiheng LIN
;
Wansheng CHEN
;
Shihong MA
;
Changqin HU
- Publication Type:Journal Article
- Keywords:
Chloramphenicol eye drops;
Ethylparaben;
Boric acid and borax;
Antimicrobial effect
- From:
China Pharmacist
2014;(5):785-788
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study whether domestic chloramphenicol eye drops with different ethylparabenin content meet the re-quirements in Chinese Pharmacopoeia. Methods:Antimicrobial effect test was used to examine the antimicrobial effect of the different eye drops. Results:The antimicrobial effect of the eye drops was in compliance with the requirements in the pharmacopoeia. Conclu-sion:The ethylparabenin concentration in the eye drops is higher than necessary. Boric acid and borax not only can adjust pH, but also show antimicrobial effect.