Effect of Jinweitai Combined with Hp Eradication Triple Therapy in the Treatment of Gastric Ulcer
- VernacularTitle:金胃泰联合Hp根除三联疗法治疗胃十二指肠溃疡疗效观察
- Author:
Xuren DONG
;
Xuewei PAN
- Publication Type:Journal Article
- Keywords:
Gastric ulcer;
Jinweitai;
Pantoprazole;
Triple therapy;
Helicobacter pylori
- From:
China Pharmacist
2014;(5):810-812
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect and safety of Jinweitai combined with triple therapy in the treatment of gastric ul-cer. Methods:Totally 140 cases of gastric ulcer patients were randomly divided into two groups, group A was given clarithromycin, amoxicillin, bismuth pectin and pantoprazole in Hp eradication triple therapy, while group B was additionally given 0. 3g Jinweitai oral-ly, po,tid. The treatment course was 8 weeks. The effect was observed and compared. Results:Both the total effective rate and Hp e-radication rate of group B were higher than those of group A, the rate of mild inflammation and non-neutrophils infiltration after the treatment in group B were higher than those in group A (P<0. 05). The incidence of adverse reactions in the two groups was without statistical significance (P>0. 05). Conclusion:Base on the conventional Hp eradication triple therapy, Jinweitai can increase Hp e-radication rate and promote inflammation eliminate without extra adverse reactions in the treatment of gastric ulcer.