Effects on blood biochemical indexes and symptoms of jaundice of plasma exchange on patients with severe hepatitis
10.3760/cma.j.issn.1008-6706.2014.07.012
- VernacularTitle:血浆置换技术对重型肝炎患者血生化指标及黄疸症状的影响
- Author:
Suying ZHANG
- Publication Type:Journal Article
- Keywords:
Plasma exchange;
Hepatitis;
Liver function tests;
Jaundice
- From:
Chinese Journal of Primary Medicine and Pharmacy
2014;(7):987-988
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of blood biochemical index and jaundice symptoms of plasma exchange on patients with severe hepatitis .Methods The clinical data of 50 severe hepatitis patients in our hospital from July 2012 to July 2013 using plasma exchange treatment were retrospectively analyzed .The patients were ana-lyzed blood biochemical changes and jaundice symptoms changes before and after treatment .Results After the treat-ment,AST,ALT,PTA,ALP,GGT,DBL,TBL,TBA and LDH were significantly decreased ,the difference was statisti-cally significant(t=7.21,7.58,4.31,11.63,10.23,8.26,4.13,16.48,7.32,all P<0.05),while TP,ALB,CHE and PA had no obvious changes;After the treatment, the jaundice symptoms of most patients disappeared or loss ,the proportion of patients with jaundice symptoms [36.0%(18/50)] was significantly lower than before the treatment (χ2 =27.06,P<0.05);The effective rate of patients with acute and subacute severe hepatitis was 70.0%(14/20), which was slightly higher than 50.0%(15/30) of patients with chronic severe hepatitis ,but the difference was not statistically significant(P>0.05).Conclusion Plasma exchange technology can effectively improve the biochemical indexes of blood of patients with severe hepatitis ,improve the symptoms of jaundice .
