Clinical value of serum tumor markers SCC and TSGF in cervix carcinoma diagnose

VernacularTitle:血清TSGF、SCC联合检测在宫颈癌诊断中的应用价值
Author: Ling MIN ; Liangxing ZHONG ; Linna CHEN ; Yuemin DENG
Publication Type:Journal Article
Keywords: Cervix carcinoma; Squamous cell carcinoma associated antigen (SCC); Tumor specific growth factor (TSGF)
From: The Journal of Practical Medicine 2014;(6):898-900
CountryChina
Language:Chinese
Abstract: Objective To explore the clinical value of squamous cell carcinoma associated antigen (SCC) and tumor specific growth factor (TSGF) in cervical carcinoma. diagnose. Methods The serum samples of SCC and TSGF were collected from 40 health volunteers, 56 cervical intraepithelial neoplasia (CIN) patients and 101 squamous cell cervical cancer patients. SCC and TSGF amount were measured by MEIA and biochemistry olorimetry method respectively, and were compared. Results The mean level of serum SCC and TSGF in the cervical cancer group was (6.95 ± 1.23) ng/mL and (81.0 ± 16.3)U/mL respectively, significantly higher than that in the CIN group and control group. The sensitivity and accuracy of combining SCC with TSGF in diagnosing cervical carcinoma were 91.1%and 87.4% respectively, both higher than allying SCC or TSGF alone. Conclusions SCC and TSGF levels are helpful in the diagnosis of cervix carcinoma. The combined determination can improve the sensitivity and accuracy of cervical carcinoma diagnose.