Quality Study of Marketed Rose Bengal Agar Culture Medium for Drug Control
- VernacularTitle:药品检验用市售玫瑰红钠琼脂培养基质量研究
- Author:
Wen XIE
;
Hongda ZHAO
;
Wenping FAN
- Publication Type:Journal Article
- Keywords:
Rose bengal agar culture medium;
Quality comparison;
Counting medium;
Drug control
- From:
China Pharmacist
2014;(5):873-875
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate overall quality status of rose bengal agar culture medium for drug control in China to provide technical support for the drug standard revision. Methods:Four quality control microorganisms, namely Aspergillus niger, Candida al-bicans, Staphylococcus aureus and Escherichia coli, were used to evaluate the quality of rose bengal agar culture medium from 7 domes-tic and foreign manufacturers. Results:Including the control medium, the pH value of all the 8 media was different. The growth rate of Aspergillus niger and Candida albicans in the seven tested media were all above 0. 7 without significant difference (P>0. 05). The selectivity factors of Staphylococcus aureus in the seven media and the control medium was more than 6. The eight media showed differ-ences in the selectivity factors of Escherichia coli. Among them, A, B, C, E, G and the control medium had no inhibitory ( selectivi-ty) , while D and F showed certain selectivity. Conclusion:The rose bengal agar media from different manufacturers for drug control show similar growth-promoting ability with different pH value and selectivity to Escherichia coli.
