New insight into fluid bolus resuscitation in pediatric severe sepsis and septic shock
10.3760/cma.j.issn.1673-4912.2014.05.017
- VernacularTitle:儿童严重脓毒症及脓毒性休克大量液体复苏的新观点
- Author:
Xian HU
- Publication Type:Journal Article
- Keywords:
FEAST trial;
Fluid resuscitation;
Sepsis;
Septic shock;
Children
- From:
Chinese Pediatric Emergency Medicine
2014;21(5):316-318
- CountryChina
- Language:Chinese
-
Abstract:
Early recognition and treatment of pediatric septic shock is key strategy to improve prognosis and reduce the mortality,yet controversy still surrounds the current fluid therapy approach.Recently,the results of the Fluid Expansion as Supportive Therapy (FEAST) trial in African children with severe febrile and hypoperfusion illnesses challenge many established principles about pediatric fluid resuscitation,and lead to intense discussion.This review is to describe the current fluid supportive therapy and possible potential mechanisms of increased death associated with bolus resuscitation.
