Retrospective analysis of the clinical outcomes in 12 recurrent borderline ovarian tumor patients with second fertility-sparing surgery
10.3760/cma.j.issn.0529-567x.2014.04.004
- VernacularTitle:卵巢交界性肿瘤复发后再行保留生育功能手术12例临床分析
- Author:
Ruifang CHEN
;
Tingting ZHU
;
Hailin YU
;
Jing ZHU
;
Xin LU
- Publication Type:Journal Article
- Keywords:
Ovarian neoplasms;
Neoplasm recurrence,local;
Reoperation;
Fertility preservation;
Pregnancy outcome
- From:
Chinese Journal of Obstetrics and Gynecology
2014;(4):254-259
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyse the clinical practicability and significance of fertility-sparing surgery for women with recurrent borderline ovarian tumors ( BOT).Methods The clinical and pathological recordings of 12 patients suffered from recurrent BOT in the Obstetrics and Gynecology Hospital of Fudan University from Jan.2002 to Dec.2012 were analyzed retrospectively.The menstruation situation , fertility function , recurrence rate and survival after second conservative surgery were collected and analyzed .Results The average onset age of these 12 patients was 26 years, and none of them had procreation before the second operation.The pathological diagnosis were still BOT and the recurrent sites of 10 patients were still restricted to the ovaries.Of the 12 cases, 8 cases of them had normal menstruation functions and 4 cases had less menstrual volumes or longer menstrual periods.Among 6 cases desired for pregnancy after the second operation,4 cases of them were successful.The spontaneous pregnancy rate was 4/6.The mean duration of follow-up was 53 months(range:23-97 months).All recurrent BOT, three cases developed recurrence once more,two cases of them were just be hinted by B ultrasounds and only one cases was approved to be BOT again by a once more surgical pathology.But no disease related deaths occurred.Conclusions The second fertility-sparing surgery may be feasible for women with recurrent BOT who are young and strongly desired for preservation of fertility.The spontaneous pregnancy rate is satisfactory.However, carefully follow-up is still needed.
