Roles of angiotensin Ⅱ receptors in tumor
10.3760/cma.j.issn.1673-422X.2014.05.001
- VernacularTitle:血管紧张素Ⅱ的1、2型受体在肿瘤中的作用
- Author:
Xiangli DING
;
Haifeng WANG
;
Delin YANG
;
Xunshi SHI
- Publication Type:Journal Article
- Keywords:
Angiotensin Ⅱ;
Neoplasms;
Receptor,angiotensin,type 1;
Receptor,angiotensin,type 2;
Angiotensin Ⅱ type 1 receptor blockers
- From:
Journal of International Oncology
2014;41(5):321-323
- CountryChina
- Language:Chinese
-
Abstract:
Angiotensin (Ang Ⅱ),a main effector peptide of the renin-angiotensin system (RAS),mediates a hormonal action in the maintenance of blood pressure and electrolyte levels,and thus fluid homeostasis.Recent studies have implicated that it correlates with tumor growth,angiogenesis,metastasis and it has drawn more and more attention.Many studies show that Ang Ⅱ-AT1R/AT2R play crucial roles in tumor growth,metastasis,invasion and tumor angiogenesis,which are formed new targets for treating malignant tumors.
