Preparation and cytocompatibility of cuttlebone-transformed hydroxyapatite
10.3969/j.issn.2095-4344.2014.16.012
- VernacularTitle:墨鱼骨转化羟基磷灰石制备及细胞相容性
- Author:
Xieshan HUANG
;
Ming LIU
;
Jiang WANG
- Publication Type:Journal Article
- Keywords:
hydroxyapatites;
durapatite;
biocompatible materials;
stents
- From:
Chinese Journal of Tissue Engineering Research
2014;(16):2532-2537
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND:Recently, bone tissue engineering is highlighted from the nature source. OBJECTIVE:To explore the preparation of a cuttlebone-transformed hydroxyapatite scaffold as the novel bone substitution. METHODS: As raw materials, the cuttlebone appeared to have a hydrothermal reaction with diammonium phosphate under specific conditions, and the hydrothermal products were characterized respectively by X-ray diffraction, Fourier transform infrared spectroscopy, energy-dispersive X-ray spectroscopy and scanning electron microscopy. RESULTS AND CONCLUSION:The results showed that the hydrothermal products were hydroxyapatite. The cuttlebone-transformed hydroxyapatite possessed good three-dimensional structure. Cytocompatibility of the cuttlebone-transformed hydroxyapatite with MG63 cels culturedin vitro were observed and we found the cuttlebone-transformed hydroxyapatite had no obvious effects on cellgrowth and no toxicity, which can be used as new bone tissue engineering scaffolds.
