To evaluate the clinical manifestations, endocrine disorders end imaging features of pituitary adenomas
- Author:
Nguyen Phong
- Publication Type:Journal Article
- Keywords:
pituitary adenomas
- MeSH:
Pituitary Neoplasms;
Diagnosis
- From:Journal of Practical Medicine
2005;517(8):52-55
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The clinical manifestations, the endocrine examinations and imaging features (MRI) of 91 patients with pituitary adenomas who had undergone transsphenoidal microsurgery from 1/2001 to 6/2003 were analyzed. The patient population was 49.5% female and 50.5% male. Mean age was 40.4 years.71 patients (78%) experienced decreased visual acuity, 67 patients (73.6) experienced headache. The most frequent tumor type was clinically nonfunctioning adenoma (50%), followed by prolactin-secreting adenoma (34.1%), growth hormone-secreting adenoma (13.2%) and last adrenocorticotropin-secreting adenoma (7.7%). there were 86 macro adenomas (94.5%) and in 13 patients (14.3%) the tumor invaded cavernous sinus. mean height was 33.05 mm, length was 26.58mm and width was 29.71mm. Conclusions: Clinical manifestations of pituitary adenomas are the result of excess hormone secretion (acromegaly, hyperprolactinemia, hypercortisolism...) and to compression of the surrounding structures (headache, visual disturbance and ocular movement palsy). The endocrine examinations are very important for diagnosis and treatment. MRI is the first choice.
