Quantitative Analysis of the Seminiferous Epithelium in Human Testis.
- Author:
Sang Kon LEE
1
;
Hee Yong LEE
Author Information
1. Department of Urology, College of Medicine, Seoul National University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
testis;
seminiferous epithelium
- MeSH:
Biopsy;
Cell Count;
Germ Cells;
Humans*;
Seminiferous Epithelium*;
Seminiferous Tubules;
Sperm Count;
Spermatids;
Spermatozoa;
Testis*
- From:Korean Journal of Urology
1986;27(4):511-517
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Number of germ cells in the seminiferous epithelium was analyzed quantitatively in testicular biopsy specimens of 23 patients without ductal obstruction and of 4 patients with ductal obstruction. Roth number of mature spermatids within each cross-section of seminiferous tubule and number of atrophic tubule were counted in biopsy specimens. Results were expressed as cell number of mature spermatids per seminiferous tubule and percentage of atrophic tubules. A significant correlation was demonstrated between sperm density and mature spermatid counts. Patients with sperm counts of less than 40 x l0(6)/ml had mature spermatids counts of less than 25 per seminiferous tubule. Coefficients of correlation between mature spermatid count and percentage of atrophic tubules were higher than those of correlation between sperm counts and percentage of atrophic tubules. In asoospermrc patients with epididymal obstruction, sperm count after corrective surgery could be predicted correctly by this quantitative analysis technique of testicular biopsy specimens and partial obstruction of anastomotic site of seminal tract could be proved in oligozoospermic patients after corrective surgery.
