Comparison of P63 Protein Expression in Non-small Cell Lung Cancer between Xuanwei and Other Regions
- VernacularTitle:P63蛋白在宣威与非宣威地区非小细胞肺癌中表达的对比研究
- Author:
Jun LIU
;
Gaofeng LI
;
Nan CHEN
;
Jun PENG
;
Xinlong CHEN
;
Ping WANG
;
Xin MAO
;
Xiangu NING
- Publication Type:Journal Article
- Keywords:
Non-small cell lung cancer;
P63 protein;
Immunohistochemistry
- From:
Journal of Kunming Medical University
2014;(1):37-41
- CountryChina
- Language:Chinese
-
Abstract:
Objective The purpose of the study was to compare the P63 expression in non-small cell lung cancer (NSCLC) between Xuanwei and other regions, and to investigate the relationship of P63 expression and biological behavior. Methods Immunohistochemical method was used. Results The results indicated that the expression of P63 in lung squamous cell carcinoma was extraordinarily high. P63 was related to the TNM staging system,tissue differentiation degree and lymph node metastasis,but not related to gender. In NSCLC,there was no significant difference of the P63 positive expression rate in the same pathological types, staging, tissue differentiation degree, lymph node metastasis and gender between Xuanwei and other regions. It indicated that the expression of P63 was not the reason why it was high incidence of lung cancer in Xuanwei region.
