Diagnosis Value of 99m Tc-MIBI-SPECT and CT Fusion Imaging in Solitary Pulmonary Nodules
- VernacularTitle:99mTc-MIBI-SPECT与定位CT融合显像诊断孤立性肺结节的价值
- Author:
Youjun ZHOU
;
Zhiyong DENG
;
Changjiang LIU
;
Gaofeng LI
;
Xudong XIANG
;
Li JIA
;
Chao LIU
- Publication Type:Journal Article
- Keywords:
Technetium Tc 99m sestamibi;
Tomography;
Solitary pulmonary nodule;
Lung cancer
- From:
Journal of Kunming Medical University
2014;(1):42-46
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnosis of value 99mTc-MIBI SPECT and CT fusion imaging in the differential solitary pulmonary nodule ( SPN). Methods Thirty-nine patients with SPN underwent 99mTc-MIBI-SPECT and positioning CT fusion imaging, and the imaging results carried on the qualitative and semi-quantitative analysis. The diagnostic value of the imaging method for SPN was judged according to the results of the final diagnosis. Results Of 39 cases with SPN, 13 cases were malignant and 26 cases were benign. The diagnostic sensitivity, specificity, accuracy, negative predictive value and positive predictive value of 99mTc-MIBI-SPECT positioning CT fusion imaging qualitative analysis in benign and malignant SPN was 92.31%(12/13),88.46%(23/26),89.74%(35/39),80% (12/15) and 95.83% (23/24),respectively. Receiver operating characteristic (ROC) curve analysis showed:using 99mTc-MIBI early uptake ratio (EUR) ≥1.474 as the critical value for identification the benign and malignant SPN, the sensitivity and specificity was 100% and 76.90%, respectively;using 99mTc-MIBI delayed uptake ratio (DUR) ≥ 1.38 as the critical value, the sensitivity and specificity was 100%and 76.90%. Conclusion The method of 99mTc-MIBI-SPECT and positioning CT fusion imaging has a high clinical value in the differential diagnosis of SPN.
