Correlation of Serum Lipoxin A4 with Clinical Grading of Chronic Hepatitis B Patients
- VernacularTitle:慢性乙型肝炎患者血浆脂氧素A4水平与疾病临床分度的关系研究
- Author:
Hui LI
;
Yongrui YANG
;
Xiaodong YANG
;
Yaling WANG
;
Yuefeng HE
- Publication Type:Journal Article
- Keywords:
Lipoxin A4;
Hepatitis B;
Hepatitis Virus B;
Clinical grading
- From:
Journal of Kunming Medical University
2014;(2):80-82
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlation between serum Lipoxin A4 and clinical grading of chronic hepatitis B patients. Method The serum Lipoxin A4 was detected by Enzyme-Linked Immunosorbent Assay in 94 chronic hepatitis B patients. Results It was found that the level of serum Lipoxin A4 of severe hepatitis patients were significantly lower than mild hepatitis patients and moderate hepatitis patients ( =0.04 and =0.03) . The serum Lipoxin A4 levels were correlated negatively with the ALT and AST levels,respectively =-0.41, =0.019 and R=-0.37,P=0.034. Conclusion These findings support the fact that the serum Lipoxin A4 may contribute to clinical grading of chronic hepatitis B patients.