Dosimetric Comparison of 6MV and 10MV Photons for Intensity-modulated Radiotherapy treatment (IMRT) of Non-Small Cell Lung Cancer
- VernacularTitle:6 MV与10 MV-X线在非小细胞肺癌中的计量学比较
- Author:
Xuhong LIU
;
Chengwen LI
;
Li WANG
;
Xiao CHEN
- Publication Type:Journal Article
- Keywords:
Non small-cell lung cancer;
Intensity modulated radiotherapy;
Dose homogeneity;
Conformity index
- From:
Journal of Kunming Medical University
2014;(2):93-96
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the effects of 6MV and 10MV-X-ray intensity modulated radiotherapy (IMRT) on non-small-cell lung cancer (NSCLC) . Methods We randomly selected 20 patients with NSCLC, 6MV and 10MV X-ray were used respectively for each NSCLC patient with IMRT plan design, the ADAC Pinnacle 8.0f treatment planning system was applied to provide the convolution/iteration algorithm, for the same target IMRT plan design with two kinds of energy. By comparing the dose volume histogram (DVH),PTV parameter (Dmean, Dmin and Dmax), conformal index (CI) and homogeneity index (HI),we analyzed the metrology parameters . Results 6MV and 10MV radiation therapy plan DVH, PTV parameters,CI,HI and isodose line was similar,no statistically significant differences. But target dose homogeneity and the degree of target coverage in high dose of 6MV plan was better than that in 10MV plan. Endanger organs (OAR) such as normal lung tissue, heart, esophagus and spinal cord had basically same dose amount. Conclusion 6MV X-ray plan may be the better choice of radiotherapy on NSCLC.
