Advances in sepsis-associated encephalopathy
10.3760/cma.j.issn.1673-4912.2014.03.018
- VernacularTitle:脓毒症相关性脑病的研究进展
- Author:
Juanjuan LYU
- Publication Type:Journal Article
- Keywords:
Sepsis-associated encephalopathy;
Delirium;
Diagnosis;
Treatment
- From:
Chinese Pediatric Emergency Medicine
2014;21(3):168-170
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis-associated encephalopathy is a diffuse brain dysfunction that occurs secondary to infection.It is characterized by alteration of consciousness and cognition,seizure or focal neurological signs.Sepsis-associated encephalopathy is accompanied by abnormalities of electroencephalogram and somatosensoryevoked potentials,increased biomarkers of brain injury and,frequently,by neuroradiological abnormalities.Its diagnosis relies essentially on neurologic examination.Hepatic/uremic encephalopathy,metabolic disturbances,drug overdose,withdrawal syndrome and Wernicke's encephalopathy are the main differential diagnosis of sepsis-associated encephalopathy.Currently,treatment consists mainly of controlling sepsis.Various drugs acting on septic pathophysiology have been tested in septic animals.
