Clinical observation of tolterodine combined with flupentixol melitracen in the treatment of patients with overactive bladder

VernacularTitle:托特罗定联合氟哌噻吨美利曲辛治疗膀胱过度活动症临床观察
Author: Youming TUO ; Shunli TANG ; Xiang CHEN
Publication Type:Journal Article
Keywords: Tolterodine; Flupentixol melitracen; Overactive bladder
From: Chinese Journal of Primary Medicine and Pharmacy 2014;21(2):202-204
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical efficacy and safety of tolterodine combined with flupentixol melitracen in the treatment of women with overactive bladder (OAB).Methods 84 female patients with OAB were chosen and randomly divided into the observation group and the control group.42 cases in observation group were treated with tolterodine combined with flupentixol melitracen.42 cases in control group were only treated with tolterodine.The clinical efficacy was recorded and compared after treatment for 4 weeks.Results The total effective rate of the observation group was higher than the control group (95.24％ vs 76.19％,x2 =6.291,P ＜ 0.05).The 24h frequency of urination,the average 24h number of incontinence episodes,initial urinate capacity and maximum bladder pressure capacity had statistically significant differences between the two groups (all P ＜ 0.05).Conclusion Tolterodine combined with flupentixol melitracen in the treatment of women with OAB has advantages of short course of treatment,excellent efficacy,and few side effects.