Nested-PCR detection of cytomegalovirus and herpesviruses 6,7 and 8 in saliva from human immunodeficiency virus-infected subjects
- VernacularTitle:HIV 感染者唾液 CMV、HHV-6、HHV-7和 HHV-8巢式 PCR 检测分析
- Author:
Chengwen LI
;
Huiping SHI
;
Jinsong BAI
;
Lei CHEN
;
Yanwei QI
;
Kaiwen DUAN
- Publication Type:Journal Article
- Keywords:
Human immunodeficiency virus;
Highly active antiretroviral therapy(HAART);
Human herpesvirus (HHV);
Nested-PCR;
Saliva
- From:
Journal of Practical Stomatology
2014;(2):265-266
- CountryChina
- Language:Chinese
-
Abstract:
CMV,HHV-6,HHV-7 and HHV-8 DNA in unstimulated whole saliva from 245 HIV-infected subjects and 30 healthy controls were examined by nested-PCR assays.Prevalence of CMV,HHV-6,HHV-7 and HHV-8 in saliva of HIV-infected subjects was 34.7%, 83.3%,70.2% and 14.3% respectively,that of the controls 10.0%,56.7%,70.0% and 0% respectively(between 2 groups,P <0.01).There was no difference of detection rates of the four HHVs in saliva between HIV patients with HAART(n =100)and non-HAART (n =145)(P >0.05).Multi-infection was observed in all subject.
