The impact of smoking on C-reactive protein level in gingival crevicular fluid before and after initial treat-ment of patients with periodontitis

VernacularTitle:吸烟对牙周基础治疗前后龈沟液中C反应蛋白水平的影响
Author: Yindi AN ; Li ZHANG ; Zheng ZHANG ; Ning MA
Publication Type:Journal Article
Keywords: Smoking; Initial periodontal therapy; Gingival crevicular fluid; C-reactive protein(CRP)
From: Journal of Practical Stomatology 2014;(2):254-256
CountryChina
Language:Chinese
Abstract: Objective:To study the impact of smoking on C-reactive protein(CRP)concentration in gingival crevicular fluid(GCF) before and after initial treatment.Methods:18 smokers and 18 non-smokers with moderate or severe periodontal disease were recrui-ted into this study.The clinical indexes of periodontal examination of the patients were recorded,GCF samples of the patients were collected,CRP level in the samples was measured by radioimmunoassay balance method before and 4 weeks after initial treatment. Results:4 weeks after initial treatment,the clinical indexes and CRP concentration in GCF of the smoking group and non-smoking group were significantly lower than those before treatment(P <0.05),the changes of the smoking group were less than those of the non-smoking group(P <0.05).Conclusion:Smoking is an unfavorable factor of the initial periodontal therapy.