The clinical application of chromoendoscopy with acetic acid and indigo carmine dye in the diagnosis of early gastric neoplasia and precancerous lesion
10.3760/cma.j.issn.1008-6315.2014.03.022
- VernacularTitle:醋酸联合靛胭脂染色诊断早期胃癌及癌前病变
- Author:
Lihua HU
;
Peng CHEN
;
Jiye ZHANG
;
Yanying WANG
;
Wenduo WANG
;
Peiyi ZHANG
- Publication Type:Journal Article
- Keywords:
Acetic acid;
Indigo carmine dye;
Early gastric neoplasia;
Precancerous lesion
- From:
Clinical Medicine of China
2014;30(3):288-290
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the significance of chromoendoscopy with acetic acid and indigo carmine dye in the diagnosis of early gastric neoplasia and precancerous lesion.Methods After conventional electronic endoscopic diagnosis,From 2011 fanuay to 300 patients of suspicious lesions were randomly divided into endoscopic dye group and control group,each was 150 cases.Patients of endoscopic dye group were directly performed biopsy after acetic acid and indigo carmine dye,while in control group were performed biopsy after only indigo carmine dye.Results In the endoscopic dye group,16 early neoplasia (10.7％),15 severe atypical hyperplasia (10.0％),79 moderate atypical hyperplasia or Intestinal metaplasia (52.7％) and 40 chronic gastritis were found.In the control group,5 early neoplasia (3.3％),10 severe atypical hyperplasia (6.7％),42 moderate atypical hyperplasia or Intestinal metaplasia(28.0％) and 93 chronic gastritis were found.Early gastric cancer and precancerous lesion detection rate of endoscopic dye was significantly higher than that of the control group,and the difference was statistically significant (P ＜ 0.001).After samples were stained with acetic acid and indigo carmine dye,the image of the mucosa of early cancer and severe atypical hyperplasia were faded mucosa,and the image of moderate atypical hyperplasia and Intestinal metaplasia was dyed asymmetrical.Chronic gastritis and normal mucosa was showed dyed equality.Conclusion Chromoendoscopy with acetic acid and indigo carmine dye improve the detection rate of early gastric cancer and precancerous lesion,thereby of high application value.
