Research progress in the effect of cirrhotic portal hypertension and its treatment on cardiovascular system
10.3760/cma.j.issn.1007-8118.2014.02.023
- VernacularTitle:肝硬化门脉高压症及其治疗对心血管系统影响的研究进展
- Author:
Shihang HU
;
Menglong WANG
- Publication Type:Journal Article
- Keywords:
Liver cirrhosis;
Portal hypertension;
Cardiovascular system;
Systemic hemodynamics
- From:
Chinese Journal of Hepatobiliary Surgery
2014;20(2):156-160
- CountryChina
- Language:Chinese
-
Abstract:
Cirrhotic portal hypertension can lead to changes in the cardiovascular system,including hyperdynamic circulation,increased cardiac output,increased splanchnic blood flow,increased heart rate,peripheral vasodilatation,decreased resistance,and a drop in blood pressure.This hemodynamic disorder not only plays an important role in the maintenance of portal hypertension,but also causes retention of sodium and water,ascites,hepatorenal syndrome,and hepatopulmonary syndrome.Recently,there is an increased interest in clinical research reports that suggest treatments for cirrhotic portal hypertension.Therapies involve internal medicine,interventional treatment,and surgery for preventing and controlling upper gastrointestinal hemorrhage,splenomegaly,hypersplenism,and other symptoms.Various treatments had some positive effects on the hyperdynamic circulatory state of the cardiovascular system.
