Relationship of adiponectin and brachial ankle pulse wave velocity in type 2 diabetes mellitus patients combined with hypertension
10.3760/cma.j.issn.1008-6315.2014.02.006
- VernacularTitle:2型糖尿病合并高血压患者血清脂联素与臂-踝脉搏波传导速度的关系
- Author:
Xiaojuan ZHAI
;
Li LI
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus;
Hypertension;
Adiponectin;
Brachial ankle pulse wave velocity
- From:
Clinical Medicine of China
2014;30(2):132-134
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship of adiponectin and brachial ankle pulse wave velocity (baPWV) in type 2 diabetes mellitus patients combined with hypertension.Methods Fifty-six patients with diabetes mellitus,69 diabetes mellitus patients combined with hypertension and 78 healthy people were recruited in our study who visited doctors in Fenyang Hospital from March 2010 to March 2012.The levels of adiponectin,brachial ankle pulse wave velocity and other biochemical indicator were determined.Analyzed the correlation between adiponectin and baPWV among the three groups.Results The levels of adiponectin in control group,diabetes mellitus group,and diabetes mellitus combined with hypertension group were (13.9 ±4.2) mg/L,(9.1 ± 3.8) mg/L and (7.6 ± 2.4) mg/L respectively,and the difference was statistically significant (F =62.53,P ＜0.01).The levels of baPWV in control group,diabetes mellitus group and diabetes mellitus combined with hypertension group were (1 617.4 ± 198.2) cm/s,(2 010.9 ±231.7) cm/s and (2 196.1 ±218.6) cm/s respectively,and the difference was also statistically significant (F =139.41,P ＜ 0.01).The correlation between adiponectin level and baPWV among three groups were-0.629,-0.561,and-0.528,respectively (P =0.027,0.034,0.029).Conclusion The levels of adiponectin decreased in diabetes mellitus patients combined with hypertension,while the baPWV increased.There is a good correlation between adiponectin and baPWV.
