Clinical study of vaccinating BCG vaccine in bronchiolitis developed into child bronchial asthma in the future

VernacularTitle:接种卡介苗对毛细支气管炎日后发展成支气管哮喘的临床研究
Author: Hong LI ; Yating WANG
Publication Type:Journal Article
Keywords: Bronchiolitis; Asthma; BCG vaccine
From: Chinese Journal of Postgraduates of Medicine 2014;37(6):16-17
CountryChina
Language:Chinese
Abstract: Objective To observe the incidence of vaccinating BCG vaccine according to plan in bronchiolitis developed into child bronchial asthma in the future.Methods Using the method of retrospective study and clinical follow-up,chosen 280 children diagnosed with bronchiolitis from January 1995 to December 2002,135 cases were vaccinated BCG vaccine according to plan (vaccinated BCG group),145 cases were not vaccinated BCG vaccine according to plan (non-vaccinated BCG group),followed up for 3-10 years,the incidence of bronchial asthma between two groups were compared.Results The incidence of bronchial asthma in vaccinated BCG group was lower than that in non-vaccinated BCG group [17.04％(23/135) vs.40.69％(59/145)],there was significant difference (P＜ 0.01).Conclusions It's easy for bronchiolitis developing into bronchial asthma in children.Vaccinating BCG vaccine in time in occurrence of bronchial asthma show a protective effect in the future.