Experiment research of vascular stimulation caused by potassium chloride and sodium chloride injection
10.3760/cma.j.issn.1672-7088.2014.05.012
- VernacularTitle:氯化钾氯化钠注射液对静脉血管刺激性的动物实验研究
- Author:
Ke LIU
;
Li HAN
;
Yahong DENG
;
Ganmi WANG
;
Junrong DU
;
Qing GAO
- Publication Type:Journal Article
- Keywords:
Potassium chloride and sodium chloride;
Sodium chloride injection;
Vascular stimulation
- From:
Chinese Journal of Practical Nursing
2014;30(5):36-39
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the potential vascular stimulation of potassium chloride and sodium chloride injection.Methods Sixteen rabbits were divided equally into two groups:group one and group two,with six rabbits in each group.According to the highest dose and maximum infusion speed for routine potassium supplementation in clinic,potassium chloride and sodium chloride injection or 0.9％ sodium chloride injection was administrated,respectively,at the same infusion speed and the same infusion volume via the marginal ear veins of rabbits.The vascular stimulation and the pathological changes of marginal ear vein and its surrounding tissue of rabbits were observed by the blinding method.Results Vascular stimulation,including hyperaemia,tumidness,necrosis and pathological changes,such as inflammatory cell infiltration and cellular necrosis,were not found in two groups.Conclusions Potassium chloride and sodium chloride injection has no stimulation to the wall of blood vessels.
