The clinical significance of B-type natriuretic peptide in the process of fluid resuscitation in the patients with severe acute pancreatitis
10.3969/j.issn.1671-8348.2014.07.011
- VernacularTitle:B型尿钠肽在重症急性胰腺炎患者液体复苏中的临床意义
- Author:
Maoxia LIU
;
Bo ZENG
;
Zhechuan MEI
;
Xiaoqiang WAN
;
Qinggui ZENG
;
Zidan ZHENG
;
Xiao XIAO
;
Qiong LIAO
- Publication Type:Journal Article
- Keywords:
pancreatitis,acute necrotizing;
natriuretic peptide,brain;
fluid resucitation
- From:
Chongqing Medicine
2014;(7):801-802
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical significance of B-type natriuretic peptide(BNP) in the process of fluid resuscita-tion with different crystalloid-colloid ratio in the patients with severe acute pancreatitis (SAP) .Methods Clinical data of 85 SAP patients were analyzed retrospectively in the Emergency Center of Chongqing during January of 2010 to December of 2012 .Early goal-directed therapy(EGDT) was confirmed the end criterion of the end point of resuscitation .Low crystalloid-colloid ratio group (n=45) and high crystalloid-colloid ratio group(n=40) were divided according to crystalloid-colloid ratio (3∶1) as the borderline , BNP were observed at the time point of before fluid resuscitation ,and 1 ,2 ,3 days after resuscitation and the day before discharge . Results Different fluid resuscitation of crystalloid-colloid ratio could improve hemodynamics in patients ,BNP increased with the to-tal amount of resuscitation liquid ,were positively correlated with liquid volume .The total amount of fluid of the high crystalloid-colloid ratio group was significantly higher than that of the low crystalloid-colloid ratio group .Conclusion BNP could guide early fluid resuscitation and low crystalloid-colloid ratio should be adopted for SAP patients .
