The meta-analysis of the value of fractional flow reserve guided percutaneous coronary intervention for patients with multivessel diseases
10.3969/j.issn.1671-8348.2014.07.019
- VernacularTitle:血流储备分数在多支血管病变患者中指导经皮冠状动脉介入治疗疗效的荟萃分析
- Author:
Mingli WANG
;
Jianping LIU
;
Li ZHONG
;
Houyuan HU
;
Luxiang CHI
;
Tao JING
;
Yonghua LI
;
Jianfeng LV
;
Shifei TONG
;
Zhiyuan SONG
- Publication Type:Journal Article
- Keywords:
fractional flow reserve,myocardial;
angioplasty,transluminal,percutaneous coronary;
vascular disease;
meta-analysis
- From:
Chongqing Medicine
2014;(7):823-825
- CountryChina
- Language:Chinese
-
Abstract:
Objective To systematically evaluate the clinical outcomes of patients with multivessel diseases treated by fractional flow reserve (FFR) guided percutaneous coronary intervention (PCI) or other forms of treatment .Methods Some keywords inclu-ding FFR or fractional flow reserve ,percutaneous coronary intervention or PCI ,multivessel coronary artery disease were used to search randomized control trails(RCT) ,which compared outcomes of patients with multivessel disease treated by FFR guided PCI with other forms of treatment ,in Chinese and English database including CNKI ,VIP ,Wanfang ,Pubmed ,EMBASE and the web of science .The quality of included studies was evaluated by Jadad quality score and all the data was analyzed by stata 10 .0 .Results A total of 7 english literatures accumulating 2024 cases in experimental group and 7 284 cases in control group were included in this study .Compared with other forms of treatment ,patients with multivessel diseases treated by FFR-guided PCI had significantly low-er risk of myocardial infarction (RR=0 .72 ,P=0 .008) .Although the risk of death and major adverse cardiovascular events were al-so be reduced ,there were no statistically significant difference .Conclusion FFR-guided PCI is an effective treatment for multivessel disease ,but it is still needs further verification for the application in Chinese population .
