Clinical application of rituximab in the treatment of immune thrombocytopenia
10.3969/j.issn.1671-8348.2014.09.020
- VernacularTitle:利妥昔单抗在治疗免疫性血小板减少症中的应用
- Author:
Wenjie YANG
;
Jinying LIN
;
Xiangying HUANG
;
Li XU
;
Huaping WEI
- Publication Type:Journal Article
- Keywords:
thrombocytopenia;
immune;
rituximab
- From:
Chongqing Medicine
2014;(9):1081-1082
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effectiviness and safety of rituximab in the treatment of immune thrombocytopenia .Meth-ods Standard doses and small doses of rituximab alone or combined therapy with other methods were used in 2 cases with immune thrombocytopenia who diagnosed and treated for the first time ,and 6 cases who diagnosed with refractory recurrent immune throm-bocytopenia .The recent curative effect ,adverse reactions were analyzed .Results The recent curative effect was well in the 2 cases who diagnosed and treated for the first time ,but 1 case recurrenced after 6 months .4 cases of effective in the 6 cases who diagnosed with refractory recurrent ,in which 1 case recurrenced after 2 years ,2 cases had no effect .All of the patients have no obvious adverse reaction in the near future .Conclusion Rituximab treatment of immune thrombocytopenic ,it is of good curative effect ,good safety and tolerability .
