The diagnostic value of quantitative analysis of dynamic contrast-enhanced magnetic resonance imaging in prostate cancer
10.3760/cma.j.issn.0254-9026.2014.01.016
- VernacularTitle:磁共振动态增强定量分析对前列腺疾病的诊断价值
- Author:
Yue CHENG
;
Qian JI
;
Yi ZHANG
;
Wen SHEN
- Publication Type:Journal Article
- Keywords:
Prostatic neoplasms;
Magnetic resonance imaging
- From:
Chinese Journal of Geriatrics
2014;33(1):55-58
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the diagnostic value of quantitative analysis parameters of dynamic contrast-enhanced magnetic resonance imaging (MRI) in differential diagnosis of prostatic disease.Methods 12 patients with prostate cancer and 16 patients with benign disease underwent DCE-MRI examination.Region of interest (ROI) were drawn in areas of cancerous foci,normal prostate peripheral zone and normal prostate central gland to measure the values of Ktrans (transport constant),Kep (rate constant),Ve (extravascular extracellular volume fraction).Values of the three parameters were analyzed by ANOVA and the differences were compared between the different tissues.Results The values of Ktrans,Kep and Ve were (0.42±0.10)/min,(0.64±0.11)/min,(0.61±0.14) respectively in the area of cancerous foci,while (0.17 ±0.08)/min,(0.32 ±0.10)/min,(0.59±0.11) respectively in normal prostate peripheral zone,and (0.33±0.12)/min,(0.50± 0.16)/min,(0.62 ±0.07) respectively in normal prostate central gland.The differences in Ktrans,Kep values were statistically significant between cancerous foci,normal prostate peripheral zone and normal prostate central gland (F =31.646,27.196,respectively,all P ＜ 0.05),but no statistically significant difference was found in the Ve value between the three different tissues (F=0.533,P＞ 0.05).Conclusions Quantitative analysis of DCE-MBI can be used to differentiate benign from malignant prostatic diseases,which hasa great application prospect.
