Clinical study on the treatment of primary trigeminal neuralgia with modified Shaoyao-Gancao decoction and carbamazepine
10.3760/cma.j.issn.1673-4246.2014.04.008
- VernacularTitle:芍药甘草汤加减联合卡马西平治疗原发性三叉神经痛的临床研究
- Author:
Yu TIAN
;
Yanwen LYU
- Publication Type:Journal Article
- Keywords:
Shaoyao-Gancao decoction;
Trigeminal neuralgia;
Primary
- From:
International Journal of Traditional Chinese Medicine
2014;(4):318-320
- CountryChina
- Language:Chinese
-
Abstract:
Objective To Observe the effects of treating primary trigeminal neuralgia with modified Shaoyao-Gancao decoction and carbamazepine. Methods 76 patients with primary trigeminal neuralgia were randomly divided into a treatment group and a control group, 38 patients in each. The treatment group was treated with modified Shaoyao-Gancao decoction and carbamazepine; and the control group was treated with carbamazepine only. Clinical curative effect, pain improvements and adverse reactions were observed after the treatment and 6 week follow-up. Results The total effective rate was 89.3%and 75.5%in the treatment group and the control group respectively, the difference was statistically significant(P=0.043). The onset frequency, duration, degree of pain were all improved in both groups after the treatment and 6 week follow-up[treatment group after the treatment is (0.54±0.78), (2.15±1.73), (1.58±1.26), 6 week follow-up is (0.24±0.63), (1.36±1.03),0.86±1.95);control group after the treatment is (1.98±1.68), (3.96±1.49), (3.02±1.45), 6 week follow-up is (1.06±1.78), (1.97±1.69), (2.13±1.54), P<0.05],and the treatment group was better than the control group(P=0.040 and 0.039 respectively). Conclusion Modified Shaoyao-Gancao decoction combined carbamazepine has good clinical curative effect in treating primary trigeminal neuralgia.
