The roles of exosomes in the tumor microenvironment
10.3760/cma.j.issn.1673-4203.2014.01.015
- VernacularTitle:Exosomes在肿瘤微环境中的作用
- Author:
Long REN
;
Zeqian YU
;
Jiahua ZHOU
- Publication Type:Journal Article
- Keywords:
Exosomes;
Tumor microenvironment;
Angiopoietins;
Neoplasm metastasis
- From:
International Journal of Surgery
2014;41(1):54-58
- CountryChina
- Language:Chinese
-
Abstract:
The tumor microenvironment is a special environment including tumor cells,stromal cells and extracellular matrix.The notion that the tumor microenvironment is a necessary functional unit to support cancer progression,metastasis and recurrence has been accepted by more and more scholars.Studies have shown that exosomes may play a pivotal role in tumor progression that involved in cell-cell communication in the tumor microenvironment.Here,we summarize the recent publications on the characteristics of exosomes,its biological effects and the potential roles as an important part of the tumor microenvironment during tumor progression.
