Matrix metalloproteinase-9 and ischemic stroke
10.3760/cma.j.issn.1673-4165.2014.01.011
- VernacularTitle:基质金属蛋白酶-9与缺血性卒中
- Author:
Limin WANG
;
Conghua JI
;
Qiang MENG
- Publication Type:Journal Article
- Keywords:
Matrix Metalloproteinase 9;
Stroke;
Brain Ischemia;
Blood-Brain Barrier
- From:
International Journal of Cerebrovascular Diseases
2014;22(1):72-74
- CountryChina
- Language:Chinese
-
Abstract:
The pathophysiological mechanism of ischemic stroke is very complex.Many intracellular and extracellular factors play the important roles in it.Studies have shown that the expression of matrix metalloproteinase-9 (MMP-9) has the changes of quantity,time and space after stroke.These changes are closely associated with the occurrence and development of ischemic stroke.The experimental studies focusing on MMP-9 also have made corresponding effects.The in-depth study of the mechanism of action of MMP-9 is expected to provide a new approach for the diagnosis and treatment of ischemic stroke.
