Characteristics of childhood BCR/ABL negative classical myeloproliferative neoplasms
10.3760/cma.j.issn.1673-4408.2014.01.021
- VernacularTitle:儿童BCR/ABL阴性的经典骨髓增殖性肿瘤的特点
- Author:
Yang WAN
;
Xiaojuan CHEN
- Publication Type:Journal Article
- Keywords:
Childhood;
Myeloproliferative neoplasms;
BCR/ABL
- From:
International Journal of Pediatrics
2014;41(1):67-71
- CountryChina
- Language:Chinese
-
Abstract:
BCR/ABL negative classical myeloproliferative neoplasms including three diseases,namely polycythemia veta,essential thrombocythemia and primary myelofibrosis.Progresses have been made in the study of these dieases in children following the development of that in adult,especially the research of molecular pathogenesis.Differences exist in clinical and molecular characteristics between children and adult BCR/ABL negative classical myeloproliferative neoplasms.There are specific characteristics in the diagnoses and treatment of childhood myeloproliferative neoplasms.This paper reviews the characteristics of childhood BCR/ABL negative classical myeloproliferative neoplasms in clinical and molecular features,diagnoses and treatment.
