Research progresses of regulatory T cells in asthma
10.3760/cma.j.issn.1673-4408.2014.01.007
- VernacularTitle:调节性T细胞在哮喘中的研究进展
- Author:
Mei SUN
- Publication Type:Journal Article
- Keywords:
Regulatory T cell;
Asthma;
Th1/Th2 cell;
Children
- From:
International Journal of Pediatrics
2014;41(1):22-25
- CountryChina
- Language:Chinese
-
Abstract:
Asthma is severely harmful to the health of the children with respiratory tract infection,but its etiology and pathogenesis is not yet entirely clear.Currently,it is considered that Th1/Th2 cell function imbalance is the immunological basis.Regulatory T cells (regulatory T cell,Treg) is one of the hot spots in recent years,regulating the immune system negatively.The decrease in the number of cells leads to immune suppression dysfunction,and creats the conditions for the development of the disease for asthma.Recent studies have found that Treg cells play an important role in the regulation of Th2 cell activation,which not only completes the traditional theories of Th1/Th2,but also provides a new method for preventing and controlling asthma by clinical use of Treg cells.
