Correlation analysis between the degree of anxiety and serum homocysteine level patients with essential hypertension
10.3760/cma.j.issn.1009-9158.2014.03.014
- VernacularTitle:原发性高血压病患者其焦虑程度与血清同型半胱氨酸水平的相关分析研究
- Author:
Meiyan LIU
;
Mei JIA
;
Mengchao LIU
- Publication Type:Journal Article
- Keywords:
Hypertension;
Anxiety;
Homocysteine
- From:
Chinese Journal of Laboratory Medicine
2014;37(3):219-221
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the correlation between the degree of anxious state in patients with hypertension and the serum homocysteine level.Methods This is a case-control study in Beijing Anzhen Hospital from January to May in 2013.164 cases of essential hypertension with continuing unstable blood pressure after being treated for nearly a week were include.They have been analysed with GAD-7 and PHQ-9 evaluation scale for anxiety and depression state.According to the anxiety status,patients were devided into three groups:Group Ⅰ (28 cases without anxiety),Group Ⅱ (81 cases with mild anxiety),group Ⅲ (55 cases with moderate-to-severe anxiety).Results (1) Correlation analysis showed,the GAD-7 anxiety scale score related with age,PHQ-9 Depression Scale and Hcy level (P ＜ 0.05),PHQ-9 Depression Scale score and Hcy levels were correlated (P ＜ 0.05).(2) Multiple stepwise regression showed that PHQ-9 Depression Scale entered the regression equation,while GAD-7 anxiety scale,age and the level of hcy were risk factors.Conclusion Hcy level is a risk factor for hypertension patients with depression,there is correlation with the severity of anxiety.Mental health should be paid attention to patients with essential hypertension.
