Efficacy of both autologous epidermal grafting and narrow band ultraviolet B radiation on stable vitiligo

VernacularTitle:自体表皮移植联合窄谱中波紫外线照射治疗稳定期白癜风的疗效观察
Author: Jingdong ZHANG ; Zhenbang DONG ; Yongzheng PAN ; Fei WANG ; Yuee ZHOU ; Jing WU
Publication Type:Journal Article
Keywords: Vitiligo; Skin transplantation; Ultraviolet therapy
From: Chinese Journal of Medical Aesthetics and Cosmetology 2014;20(1):30-32
CountryChina
Language:Chinese
Abstract: Objective To evaluate the efficacy of the autologous epidermal grafting combining with NB-UVB radiation on the treatment of stable vitiligo.Methods Autologous epidermal graft acquired by suction blister under negative pressure were transplanted onto the laser-abraded depigmented areas,then the narrow-band UVB radiation was given after grafting to 35 patients with stable vitiligo.The onset time and the area repigmentation of every epidermal graft 3 months latter were observed (digital image contrasted before and after treatment).The results were compared with 37 cases only treated with autologous epidermal grafting.Results Both onset time and the cure rate in combined treatment group were statistically significant (P＜0.05) as compared with control group.Conclusions The combination of autologous epidermal grafting with NB-UVB radiation can shorten the onset time of repigmentation and promote generation and extension of the melanin.