131I treatment of differentiated thyroid carcinoma in children and adolescents
10.3760/cma.j.issn.2095-2848.2014.01.025
- VernacularTitle:儿童和青少年分化型甲状腺癌的131I治疗
- Author:
Yuan QU
;
Rui HUANG
;
Lin LI
- Publication Type:Journal Article
- Keywords:
Thyroid neoplasms;
Radiotherapy;
Iodine radioisotopes;
Child;
Adolescence
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2014;34(1):76-78
- CountryChina
- Language:Chinese
-
Abstract:
The occurrence rate of DTC in children and adolescents is not high.However,DTC in these patients has some distinct characteristics different from those in adult,such as larger tumor volume at diagnosis,early invasion of neck lymph nodes and early distant metastases,high NIS expression,high recurrence but higher overall survival rate.131 I ablation is still one of the important treatment methods after surgery.Currently,there are 3 major dosage regimens adopted for 131I treatment: prescribed dose without causing bone marrow suppression/toxicity,dose aiming at tumor ablation,and empirically fixed dose.
