Effect of intracavitary therapy on acute pulmonary embolism
10.3760/cma.j.issn.1008-6315.2014.02.021
- VernacularTitle:急性肺栓塞的腔内治疗效果观察
- Author:
Qingxu GUO
;
Liguo YANG
;
Yunlong LIU
;
Chuang MA
- Publication Type:Journal Article
- Keywords:
Pulmonary embolism;
Intracavitary therapy;
Pulmonary artery;
Thrombolysis
- From:
Clinical Medicine of China
2014;30(2):180-182
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of intracavitary therapy on acute pulmonary embohsm.Methods Fifteen patients were selected as our subjects,who suffered acute pulmonary embolism and received percutaneous catheter thrombus crashing and catheter directed thrombolysis in Beijing Military.Region General Hospital from January 2009 to June 2011.Local injection of Urokinase was performed with a total amount of 500 000 U in catheter directed thrombolysis.After thrombolysis,low molecular Heparin was administered to patients for 7-10 days and oral administration of Warfarin was performed for 3-6 months.Clinical symptoms,improvement of physical signs,complications,changes of mean pulmonary arterial pressure(mPAP) and arterial partial pressure of oxygen(PO2),and the opening of pulmonary artery were recorded.Results The pulmonary arteries of the 12 patients were completely opened,and partially opened in 3 patients.The effective rate was 100％ (15/15).mPAP was reduced from (40.07 ±5.97) mmHg to (20.00 ±4.66) mmHg (t =-1.128,P ＜ 0.05),PO2 was increased from (50.26 ± 9.30) mmHg to (80.49 ± 9.04) mmHg (t =1.246,P ＜ 0.05).Patients were followed-up for 3-6 months and no recurrence case was seen.Conclusion The interventional therapy is effective,safe and practicable in the treatment of acute pulmonary embolism.
